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Methods From the US-based OPERA cohort, treatment-experienced adults with HIV who switched to a DOR-containing regimen between 30AUG2018-30NOV2022 with a viral load 45 days without ART, (c) 12 months after last clinical contact, (d) death, or (e) study end (31MAY2023)

This is a compound that shifts systemic methylation balance and NAD+ economy, and nobody has published what that looks like in humans over months or years