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doi: 10.1016/J.JFCA.2021.104226 228

Blockade of the microglial P2X7 receptors or administration of minocycline, which has potent anti-inflammatory properties, has been shown to attenuate the production of these inflammatory mediators and alleviated chronic pain symptoms caused by neuronal hyperexcitability in the spinal dorsal horn (Chu et al., 2010