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J Biol Chem 253:27692776 Rom WN, Basset P, Fells GA et al (1988) Alveolar macrophages release an insulin-like growth factor I-type molecule

It is overexpressed in the adipose tissue of obese and diabetic individuals

In this trial, the dosage of colchicine was 0.5 mg once daily for patients weighing up to about 154 pounds and 0.5 mg twice daily for those weighing over 154 pounds