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Furthermore, oil red staining, Prussian blue staining, and transmission electron microscopy (TEM) analyses showed the presence of numerous lipid droplets and perilipin-positive areas, substantial accumulation of free iron ions, and pronounced alterations in mitochondrial cristae structure in the muscle tissue of the oe-FOXO1 + sh-NC group

Pulmonary Absorption: Audio Overiew (2025) Pulmonary drug absorption represents an important route of administration that leverages the unique anatomical and physiological characteristics of the respiratory system for both local and systemic drug delivery

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Specifically, increase of caspase-9, apoptosis, mitochondrial reactive free oxygen species (fROS), lipid peroxidation, glutathione (GSH), transient receptor potential vanilloid-1 (TRPV1) current density, and calcium concentrations in the DRG and hippocampus was detected in STZ-induced diabetic peripheral mechanical allodynia and thermal hyperalgesia (Siniscalco et al., 2008)