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This would imply the accumulation of serine that is very important for glycine synthesis and the activity of folate and methionine cycles, in order to supply the synthesis of nucleotides and methyl groups, respectively, needed for cell proliferation and epigenetic regulation

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doi: 10.1016/j.cmet.2017.03.017 96 SalomonDMedaP

[DOI] [PubMed] [Google Scholar] 29.Bizovi KE, Smilkstein MJ