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Contraindications, Drug Interactions, and Monitoring Important precautions include: Avoiding use in active, untreated malignancies due to theoretical tumor-promotion concerns Using caution with immunosuppressants Monitoring blood pressure and liver enzymes if treatment exceeds six weeks Consulting a healthcare professional if you have bleeding disorders or take anticoagulants Bodybuilders who use multiple compounds should be especially careful because side effects and interactions may be harder to identify

25 As scientific understanding evolved in the late 20th century, research revealed that ROS, especially H 2 O 2 , are not only destructive agents but also essential regulators of cellular signaling

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doi:10.1016/j.cvsm.2017.12.005