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A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity

10.1007/s12011-021-03011-7 94 ZhengK.ZengZ.TianQ.HuangJ.ZhongQ.HuoX

321 Ligandreceptor binding results in the release of the Notch intracellular domain (NICD) and NICD interaction with recombination signal-binding protein immunoglobulin kappa J (RBPJ) to initiate the transcription of downstream target genes such as HES/HEY