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Description

Transgenic (Tg) mice that overexpress IGF-I in the brain exhibit postnatal brain overgrowth without anatomic abnormality (up to 85%) via an increase in cell number[83] and myelination[84]

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Then, we used the AMPK inhibitor compound C (CC) and found that the therapeutic effect of TP-10@CaP-CTP on cardiac hypertrophy was blocked by CC, as indicated by the CM cell surface area (Fig