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the molecule may not be absorbed effectively in the digestive tract the dose may be too small to influence cellular physiology the compound may break down before reaching target tissues the body may rapidly eliminate it through the liver or kidneys Even when a compound is absorbed into the bloodstream, that does not necessarily mean it will influence cellular biology

Methods Rats and surgical procedures All studies were carried out in accordance with the NIH Guide for the Care and Use of Laboratory Animals (NIH Publication No

Elango, T., Jeyaraj, A., Dayalan, H., Gnanaraj, P., Li, X., & Zhang, X

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