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10.1074/jbc.274.11.6831 102 KramerH

Rewiring cell signalling pathways in pathogenic mtDNA mutations

We, therefore, speculate that these signaling differences between DA and NE may provide islet cells with an additional mechanism for finer temporal control of hormone release that may be especially critical for differential metabolic adaptations to states of acute and chronic stress when concentrations of circulating catecholamines are altered