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Vitamin C boosts your immune system and fights oxidative stress

doi:10.1007/s00335-011-9387-6

Arch Biochem Biophys 111:593602 Andreadou I, Menge WMPB, Commandeur JNM, Worthington EA, Vermeulen NPE (1996a) Synthesis of novel Se-substituted selenocysteine derivatives as potential kidney selective prodrugs of biologically active selenol compounds: evaluation of kinetics of -elimination reactions in rat renal cytosol

proposed that thiamine supplementation may be indicated for all children with ASD (149), with the idea that heavy metal toxicity can hamper TKT activity, increase oxidative stress, and, in turn, disrupt thiamine homeostasis