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Statistical analysis Data are given as means standard deviation (SD)

Solid-phase extraction-based methods SPE is a preferred method for trapping analytes and separating them from the sample matrix, addressing the disadvantages of LLE such as excessive solvent use and prolonged operation times (Badawy et al., 2022

While direct trials pairing Lipo C with semaglutide or tirzepatide remain limited, metabolic studies confirm that adequate B vitamin status supports cellular energy efficiencya logical complement to appetite-suppressing GLP-1 therapy