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Typically, the person performing the therapy must be, at minimum, a licensed physical therapist

reported side effects include: headache hypertension Drug Interactions: may cause hypertension if given with other pressor agents References: Biaggioni I (2021): Adrenoceptor Agonists & Sympathomimetic Drugs (Chapter 9)

Additionally, in this group, a linear relationship existed between the observed change in CNFD and the change in symptoms for the ARA 290 subjects as assessed by PainDetect (Figure 6)