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Moreover, the accumulation of ROS can activate autophagy, the cellular process of self-digestion to degrade and recycle damaged components, and excessive autophagy can also result in cell death

Instead, they act as both direct building blocks for repairing micro-tears in the muscle fibers and as powerful signaling molecules that command the body to initiate structural tissue synthesis

and J.J.T

The in vitro model of PC12 cells induced by A25-35 showed that the viability of PC12 cells was significantly decreased, and the levels of oxidative stress and apoptosis were increased, suggesting that the occurrence of AD may be closely related to oxidative stress and apoptosis caused by A deposition