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10.1038/s42255-020-00338-8 156 NitzK.LacyM.AtzlerD

Therapeutic targeting of PFKFB3 with a novel glycolytic inhibitor PFK158 promotes lipophagy and chemosensitivity in gynecologic cancers

Through EMT, epithelial cells lose cell polarity, connections to the basement membrane and other epithelial phenotypes, and gain mesenchymal phenotypes such as increased migratory and invasive abilities, anti-apoptotic features and the capacity to degrade the extracellular matrix (79)

2005 Remakova M, Skoda M, Faustova M, Mann H, Krystufkov O, Vencovsky J, Novota P: Gene regulation and signaling: The expression regulation of the HSPA1B gene in patients with myositis is not dependent on the presence of HLA-DRB1*03 risk allele