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10.1007/s10495-022-01714-3 54 ZhouM.YuY.LuoX.WangJ.LanX.LiuP.et al (2021)

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An 8-week randomized double-blind clinical trial comparing GHK-Cu in nano-lipid carrier to Matrixyl 3000 showed 55.8% reduction in wrinkle volume versus control serum and 31.6% reduction versus Matrixyl 3000, with 32.8% reduction in wrinkle depth versus control

Compared with healthy adults, PD patients exhibit significant -syn deposition in cutaneous autonomic nerve fiber terminals, with notably higher levels in the scalp and cervical skin than in other sites [96]