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Researchers should establish concentration-response curves early in their study design to identify the relevant working range for their specific model system

[DOI] [PMC free article] [PubMed] [Google Scholar] 56.Lee T.W., Bae E., Kim J.H., Jang H.N., Cho H.S., Chang S.H., Park D.J

Nature 409 : 194198 Tschop M et al

Given that Trkb Penk -KO mice suffer from subtle deficits in their gait caused by reduced motor control 13 , we first scored mutants and controls at 34 months for supported and unsupported rearing