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Disease activity was assessed as previously described 56

significant changes in the signal intensity induced by the tyrosine and tryptophan metabolites were observed, especially from the noradrenaline, adrenaline pathways, and serotonin metabolism as well as lipid peroxidation ( In the pathway of tyrosine metabolism, most of the experimental metabolites identified come from the adrenaline and noradrenaline degradation subpathway

It has been demonstrated that the expression of the purine-free/pyrimidine-free nucleic acid endonuclease 1 (APE1) is downregulated in gastric host cells infected with H

In vitro studies have indicated that DHEA directly inhibits the proliferation and promotes apoptosis of human ovarian granulosa tumor cell line (KGN) cells by down-regulating IFN- expression via the activation of the PI3K/AKT signaling pathway (147)