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Similar to rapamycin [32] , via blockade of mitochondrial oxidative stress and mTOR [10,33] , NAC may have the premise to expand antiviral CD8 T cells and reverse infections [8] and thus potentially expand life-span in SLE [34]

The therapeutic dosage of Glutathione may vary depending on an individual's age, weight, detoxification needs, and wellness goals

NRF2 orchestrates the upregulation of several antioxidant genes reliant on GSH, including GSR, solute carrier family 7 member 11 (SLC7A11), glutamatecysteine ligase catalytic subunit (GCLC), and glutamatecysteine ligase modifier subunit, as well as metabolic detoxification genes such as aldehyde dehydrogenase 1 family member A1 and aldoketo reductase family 1 member C1 in cancer cells [66]

Hydration and Recovery Caffeine acts as a mild diuretic, which can increase fluid loss