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Furthermore, RES has been found to significantly suppress glutamate-induced currents in postsynaptic CA1 pyramidal neurons, with kainate and NMDA receptors being more sensitive to RES compared to AMPA receptors [124]

For the extracellular acidification rate (ECAR) assay, the following reagents were sequentially added: (a) glucose (10 mM), which increases glycolysis

The drug accumulates in cochlear cells, particularly in stria vascularis and OHC, leading to irreversible apoptosis

It is commonly used to investigate cellular communication, structural biology, and complex signaling pathways in controlled laboratory environments