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A combination of polyphenols such as anthocyanins, flavonols, and derivatives of phenolic acids can reduce the expression of miR-103 [192]

Cells have developed a sophisticated antioxidant system to protect against these oxidative insults, consisting of enzymes that either convert superoxide radicals into hydrogen peroxide (H 2 O 2 , SOD1, and catalases) or H 2 O 2 into water and oxygen [peroxiredoxin (Prx) and glutathione peroxidase (GPx)

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Thereby, the reduced glutathione works as an antioxidant to neutralize reactive oxidative species (ROS) via electron donation [1]