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We speculate this cooperative action ensures a robust and multi-layered defense against CHIKV

doi: 10.1186/s12885-021-08303-8 51 SilzleTBlumSKasprzakANachtkampKRudeliusMHildebrandtBet al

This was followed by the phase II KEYNOTE-086 of single-agent pembrolizumab in mTNBC, which found an ORR of 21% when used in the first line for PD-L1 positive disease, and a more modest ORR of 5.7% after the first line in any level of PD-L1 expression [33, 34]