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46 Pulmonary fibrosis (PF) is a common, progressive, irreversible, and fatal chronic lung disease characterized by excessive structural remodeling of lung tissue due to myofibroblast proliferation and extracellular matrix deposition that impairs alveolar elasticity and lung function, ultimately leading to severe functional failure and even death

R.ShaniY.et al (2023)

Additionally, BPC-157 activates signal pathways involving Src, caveolin-1 (Cav-1), and eNOS, while reducing protein-protein interaction between eNOS and Cav-1, thereby enhancing nitric oxide bioavailability

[DOI] [PMC free article] [PubMed] [Google Scholar] Ying W