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Furthermore, the integration of genomic and transcriptomic profiling to develop refined IFN-related gene signatures holds significant potential for pretreatment patient stratification, enabling the identification of individuals who are likely to benefit from enhanced IFN signaling, as well as those whose tumor microenvironments may already be characterized by chronic IFN exposure and associated immunosuppressive effects

Li et al (2) analyzed Thymocid , a standardized TQ extract, which can inhibit the formation of advanced glycation end products, collagen cross-linking, collagenase and elastase activities in vitro

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doi:10.1136/bmjopen-2022-060972 37 Wu JM, Ho TW, Lai IR, Chen CN, Lin MT