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2018;104(Suppl 6):A434

Its deficiency causes calcium build-up promoting the release of substance P, a neuropeptide involved in immune response and inflammation resulting in oxidative stress (Weglicki et al., 2011)

Folate and B12 are involved in one-carbon metabolism and help create S-adenosyl-methionine (SAM), a key player in producing serotonin and dopamine [31]