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Owing to their diverse etiologies, onset ages, and potential repair mechanisms, the discovery of new treatments for treating myelin pathologies should aim at globally stimulating endogenous oligodendrogenesis, known to spontaneously increase following injury, at multiple levels, i.e., from the specification of new OPCs from neural progenitor cells (NPCs), to the maturation of pre-existing ones within the parenchyma

Computational prediction of human disease- associated circRNAs based on manifold regularization learning framework

Addressing these areas will not only deepen the understanding of ferroptosis in LN but also facilitate the development of precise, translatable biomarkers and therapies for this severe autoimmune kidney disease

The top five precursor ions were subsequently fragmented, in a data-dependent manner, using the higher energy collisional dissociation cell set to 30% normalized collision energy in MS2 at a resolution power of 17,500