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While the diversity in 5-ALA administration methods and preparation formulations will lead to different tumor accumulation peaks of PpIX, the biodistribution of PpIX, metabolic kinetics, and intratumoral sO 2 levels before and after laser exposure are also variable due to tumor heterogeneity

SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress

HDLs are heterogeneous density lipoproteins with varying size and composition

Bartizal: employees and ownership interests, Cidara Therapeutics P579 Phase 2b, Randomized, Double-Blind, Placebo-Controlled Trial of Presatovir for treatment of Hematopoietic-Cell Transplantation (HCT) Patients with Respiratory Syncytial Virus (RSV) Lower Respiratory Tract Infection (LRTI) Sanjeet Dadwal 1 , Roy Chemaly 2 , Anne Bergeron 3 , Per Ljungman 4 , Yae-Jean Kim 5 , Michael Boeckh 6 , Alpana Waghmare 6 , Kathleen Mullane 7 , Dong-Gun Lee 8 , Catherine Small 9 , Hans Hirsch 10 , Elodie Blanchard 11 , Roberto Patron 12 , Matt McKevitt 13 , Danielle Porter 13 , Robert Jordan 13 , Ying Guo 13 , Polina German 13 , Timothy Watkins 13 , Jason Chien 13 , Francisco Marty 14,15 1 2 3 4 5 6 6 7 8 9 10 11 12 13 13 13 13 13 13 13 14,15 1 City of Hope National Medical Center, Duarte, CA, United States