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On the physiological level, GSH is in high concentration in cells and can effect transport processes that control arsenic uptake and removal from cells, as well as the availability of other thiols

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Exposure to glutamate leads to a decrease in GSH levels and an accumulation of intracellular peroxides, resulting in oxidative stress and cell death ( As talked about previously, tumor-associated immunotherapy studies have shown that CD8 + T cells enhance ferroptosis-specific lipid peroxidation in tumor cells