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It directly targets GSH depletion in hyperglycemia, producing outcomes measurable at the cellular immune level

[DOI] [PubMed] [Google Scholar] 150.Jeong HC

Gex1 is a yeast glutathione exchanger that interferes with pH and redox homeostasis

This might be inclusion of the effect of the cytoplasmic aqueous surroundings (on enzyme activity in particular, and cellular biochemistry in general), in stabilising protein structures