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As ischemia progresses, it can be further divided into three phases according to the events occurring in the affected tissue: acute (or initial), subacute (intermediate), and chronic (late) phase (Andreeva et al., 2014

Collectively, these findings suggest that ferroptosis plays a pivotal role in the pathogenesis of PA-induced pediatric pneumonia, highlighting the potential for therapies targeting iron homeostasis or ferroptosis inhibition as novel strategies for managing this condition