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The second isocratic step of the elution gradient was purposely extended far beyond the elution of vicine and convicine (i.e., until 14 min), since this enabled an improvement of the separation between them and other polar compounds contained in the flour extract, whose peaks were clearly detected in the LC-ESI-MS Total Ion Current (TIC) chromatogram obtained for the flour extract, also shown in Fig

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Furthermore, QFPDD suppressed the activation of M1 macrophages and reduced the levels of IL-6, TNF-, MIP-2, MCP-1, and IP-10 while increasing IL-10 expression, as reported by Ye et al

Pickart seal en sus estudios cientficos que GHK-Cu aborda los signos del envejecimiento que comienzan a ocurrir a partir de los 20 aos