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IP was induced by daily oral administration (3 g/g weight) of MTX using a feeding needle (Thermo Fisher Scientific, Waltham, MA), as indicated in Table 2

The ratio of OPA1 isoforms correlates with mitochondrial structure, where an increase of short isoforms is associated with mitochondrial fragmentation (Fig

Gently massage in circular motions until a lather forms, then rinse well with warm water

However, the therapeutic efficacy of antidepressants varies considerably among individuals and proves ineffective for many patients with major depressive disorder, resulting in frequently unsatisfactory recovery rates (Fox and Lobo, 2019)