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72 These findings suggest that subnormal ALP levels may be a useful diagnostic tool for HPP, that PLP levels may be useful in patients with a suspected diagnosis of HPP, for screening family members to detect possible heterozygotes, and to monitor response to therapy

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Bordone L, Cohen D, Robinson A, Motta MC, van Veen E, Czopik A, Steele AD, Crowe H, Marmor S, Luo J, et al