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In oxygen-rich regions, LDHB catalysis in oxidative cancer cells results in the conversion of lactate to pyruvate, which then enters the TCA cycle together with NADH via the malateaspartate shuttle

[DOI] [PMC free article] [PubMed] [Google Scholar] 92.Zangabad P.S., Mirkiani S., Shahsavari S., Masoudi B., Masroor M., Hamed H., Jafari Z., Taghipour Y.D., Hashemi H., Karimi M