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Combination therapy should only be reviewed by a licensed provider because dosing, monitoring, and safety risks become more complex

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Cortisol is a stress hormone, and while a transient increase might not be problematic, sustained high levels can have metabolic consequences

373,374 They regulate the expression of oncogenes and tumor suppressor genes through various mechanisms, including acting as miRNA sponges to adsorb miRNAs or binding to RNA-binding proteins (RBPs) to form complexes, thereby affecting gene transcription