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Am J Kidney Dis 37(2):400410 Quiles JL, Martnez E, Ibez S, Ochoa JJ, Martn Y, Lpez-Fras M, Huertas JR, Mataix J (2002) Ageing-related tissue-specific alterations in mitochondrial composition and function are modulated by dietary fat type in the rat

[13] The entire clinical management of Wilsons disease is aimed at removing copper and restricting its intake, so any molecule whose function is to deliver copper systemically runs directly counter to that goal

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Overall, the ECMS and imECMS represent the most robust classification systems currently available for ESCC, laying a foundation for future clinical stratification and subtype-based targeted interventions