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Furthermore, H&E staining showed that compared to the aorta of normal aging mice, the aorta of mice treated with FOXO4-DRI was thinner, and the PWV value was lower in the ultrasound detection results, which means that the mice treated with FOXO4-DRI had better vascular elasticity and better vascular function than normal aging mice (Figures 1D,E)

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We also accessed the effect of NAC in gpx-5(tm2024) , which appeared to have a low lipid oxidation level and normally showed a high fusion rate and a low debris rate

VDAC was demonstrated to be able to dictate cell death and survival, that is, a decrease in VDAC reduces cell viability