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Description

Clinical trial data extend to 2-3 years of continuous use with no significant safety concerns emerging

More commonly, I see it in combination with iron deficiency and sometimes folate deficiency

Initially, it received FDA approval for treating type 2 diabetes

In a study of patients with chronic low back pain, Vitamin B12 given for 2 weeks reduced pain by 32% compared to placebo [Chiu, 2011] In a 2020 systematic review looking at the use of B12 for nerve-related pain it was found that there is moderate evidence for the therapeutic effect of B12 in the treatment painful peripheral neuropathy [Julian, 2020]