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Identification of a tumour immune barrier in the HCC microenvironment that determines the efficacy of immunotherapy

Study participants included in one or more analyses had been enrolled in selected insurance plans or health systems for at least one year, were free of at least one outcome at baseline, completed a minimum number of follow-up assessments, and either: 1) filled multiple extended-release/long-acting opioid analgesic prescriptions during a 90 day period (n=978)

doi: 10.1002/cncr.22386

Higher doses may be needed to treat certain chronic and degenerative diseases, including COPD, impaired glucose control and cancer