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Surface modification Surface modification or conjugation of active functional groups to nanoparticles is another strategy to modulate their permeability to the BBB when optimizing the nanoparticles' own physicochemical properties is not sufficient to achieve the desired effect

As the feasibility of large-scale production, for example, the size and shape, ratios of the weight and volume to the reaction volume, and stirring conditions employed in this study would be reproducible when increasing the reaction volume to 1,000 mL for repeated batch reactions of NsPCS immobilized on both the cellulose sponge and MCC

Gene Expr Patterns 7(4):485490 Chan PH, Fishman RA (1978) Brain edema: induction in cortical slices by polyunsaturated fatty acids

PMID:33485880