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Inhibition of human erythrocyte isozymes I and II with a series of phenolic acids

The most common side effects of chronic vitamin A toxicity are: Vision problems Joint and bone pain Loss of appetite Nausea and vomiting Sensitivity to sunlight Hair loss Headaches Dry skin Liver damage Jaundice Delayed growth Decreased appetite Confusion Itchy skin Toxicity can adversely affect the health of pregnant women and their babies and may lead to fetal developmental abnormalities

Neither of these eminent scientists could have known that their conjecture about the absence of senescence in the wild would be thoroughly disproven by field studies in the 1990s, The definitive recent work on this subject is [Jones, 2014]

Expression of the Neural REST/NRSF-SIN3 Transcriptional Corepressor complex as a target for small-molecule inhibitors