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Patel SP, Michael FM, Arif Khan M, Duggan B, Wyse S, Darby DR, et al

154 Selective inhibitors of MMP-9 are also being developed and have proven to be effective in treating COPD in animal models, but have not been effective in clinical trials of COPD

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These results were further verified by in vivo data showing that xenograft tumor growth was apparently delayed by treatment with combined GO203 and Mdivi-1 compared to individual inhibitors (Fig