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Eur J Pharmacol 479:249262 Aragn C, Lpez-Corcuera B (2005) Glycine transporters: crucial roles of pharmacological interest revealed by gene deletion

The in vitro affinity maturation has successfully been used to optimize antibodies, antibody constructs, and antibody fragments

While the cellular roles of UBE3A are not fully understood, studies suggest that the lack of UBE3A function is associated with elevated levels of reactive oxygen species (ROS)