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2.3.1 Curcumin Curcumin, the principal polyphenol from Curcuma longa, suppresses PsO-related inflammation by inhibiting IB kinase, thereby preventing NF-B activation and downstream cytokine transcription [40] In murine imiquimod (IMQ) models, curcumin reduces epidermal hyperplasia and attenuates IL-17 and IL-23 signaling

The 0.5mg group achieved 10.6% mean weight reduction

Glutathione is injected directly into the bloodstream using a needle, producing immediate effects

The BDNF increase from fasting appears to be related to the switch from glucose to ketone metabolism, as ketone bodies like beta-hydroxybutyrate directly stimulate BDNF gene expression in the hippocampus