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Statements Authors note Some data and figures presented in this manuscript were previously presented as an abstract at the American College of Veterinary Pathologists Annual Meeting 2019 in San Antonio, TX and in the Journal of the Federation of American Societies for Experimental Biology (45)

A GST-tagged HRV-3C-protease produced in house 39 was added in a mass ratio of 1: 50 (protease: protein) and the mixture was placed at 4 C for 40 hours

,, This combination is still under investigation in clinical development programs to better understand how simultaneous activation of amylin-related and GLP-1-related pathways influences biological outcomes