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Metabolic gene expression and epigenetic effects of the ketone body -hydroxybutyrate on H3K9ac in bovine cells, oocytes and embryos

The mGlu2/3 receptor inhibitor LY341495 disodium salt (Tocris Cookson Limited, Bristol, UK) was dissolved in 66 mM phosphate-saline buffer (pH 8.0) and administered intraperitoneally (i.p.) at a dose of 1 mg/kg per day (delivered as 5.0 ml/kg), as previously reported (Fukumoto et al., Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Lipoxin A4 (stock ethanol solution 25 g/250 l

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