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Description

At age 20, concentrations are much higher than they are by age 60, which correlates with slower healing, reduced skin quality, and diminished hair health

Discontinue and reassess if shedding seems disproportionate to expected adjustment

Less rigorous than a prospective randomised trial but useful for generating preliminary evidence

The reaction time was defined by placing the mouse on the hot plate, and the time was recorded when the animal showed hind paw licking or jumping, and the 45 sec period was observed to avoid tissue damage