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As well as being a potent antioxidant, glutathione also plays a detoxifying role in the body, particularly in the liver where it helps eliminate heavy metals such as mercury and lead

Vo TTT, Peng TY, Nguyen TH, Bui TNH, Wang CS, Lee WJ et al (2024) The crosstalk between copper-induced oxidative stress and cuproptosis: a novel potential anticancer paradigm

What has been reported in the available human pilot research is that no significant adverse effects were observed - which is a meaningful data point for safety consideration, even if it does not establish efficacy by clinical standards

Knockdown of GCH1 significantly activated ferritin autophagy upon erastin treatment, which was reversed by using an autophagy inhibitor