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This cascade of oxidative damage and barrier dysfunction is increasingly recognized as a core mechanism linking neuroinflammation to the neurodevelopmental abnormalities observed in ASD (Russo et al., 2018)

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injection with KDS12008 (3 mg/kg/day), KDS12017 (3 mg/kg/day), or KDS12025 (3 or 10 mg/kg/day) once per day for 1 or 2 weeks, depending on the experimental protocol