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This mechanistic defect highlights the importance of not expanding Treg numbers but of restoring IL-2R signal fidelity

Finally, we showed that Put can be converted to GAB via a diamine oxidase (DAO)-dependent reaction as its inhibitor aminoguanidine (AG) completely blocked the production of [ 13 C 4 ]GAB from [ 13 C 4 ]Put (Fig

Iliodromiti S et al (2010): Methyldopa in clinical practice

EW macrophages have a decreased ability to adhere when compared with the control group, but glutamine supplementation at 1 and 2 mM were capable of reversing this effect